David Ricks, chief govt officer of Eli Lilly & Co., throughout a information convention at Technology Park in Houston, Texas, US, on Tuesday, Sept. 23, 2025.
Mark Felix | Bloomberg | Getty Photos
Eli Lilly on Thursday reported third-quarter earnings and income that topped estimates and hiked its full-year outlook, as the corporate continued to see robust demand for its blockbuster weight reduction drug Zepbound and diabetes therapy Mounjaro.
Shares of the corporate rose 5% in premarket buying and selling Thursday.
The pharmaceutical big now expects its fiscal 2025 income to return in between $63 billion and $63.5 billion, up from a earlier steerage of $60 to $62 billion. Eli Lilly additionally expects full-year adjusted revenue to return in between $23 and $23.70 per share, up from its earlier outlook of $21.75 to $23 a share.
Eli Lilly stated the steerage displays President Donald Trump’s present tariffs as of Thursday, however doesn’t embody his threatened levies on prescribed drugs imported into the U.S.
Mounjaro raked in $6.52 billion in income for the quarter, up 109% from the identical interval a 12 months in the past. That blew previous the $5.51 billion that analysts have been anticipating, in response to StreetAccount.
Zepbound, which entered the market roughly two years in the past, posted $3.57 billion in income for the third quarter. That is up 184% from the year-earlier interval and barely forward of the $3.5 billion that Wall Avenue was anticipating, in response to StreetAccount estimates.
Here is what Eli Lilly reported for the third quarter in contrast with what Wall Avenue was anticipating, based mostly on a survey of analysts by LSEG:
- Earnings per share: $7.02 adjusted vs. $5.69 anticipated
- Income: $17.60 billion vs. $16.01 billion anticipated
The outcomes come as Eli Lilly works to take care of its edge over chief rival Novo Nordisk within the booming marketplace for a category of weight problems and diabetes medication known as GLP-1s.
The corporate posted third-quarter income of $17.60 billion, up 54% from the identical interval a 12 months in the past.
Gross sales within the U.S. jumped 45% to $11.30 billion. Eli Lilly stated that was pushed by a 60% improve in quantity — or the variety of prescriptions or models offered — for its merchandise, primarily for Mounjaro and Zepbound. That was partially offset by decrease realized costs of the medication, the corporate stated.
The pharmaceutical big booked web earnings of $5.58 billion, or $6.21 per share, for the third quarter. That compares with web earnings of $970.3 million, or $1.07 per share, a 12 months earlier.
Excluding one-time gadgets related to the worth of intangible belongings and different changes, Eli Lilly posted earnings of $7.02 per share for the second quarter.
The outcomes underscore Eli Lilly’s robust benefit within the booming GLP-1 drug market.
The corporate has gained the bulk market share over the past 12 months, because of the robust profile of its weight reduction and diabetes injections and a lift from its direct-to-consumer gross sales, amongst different efforts. Eli Lilly took one other stride to spice up entry to Zepbound on Wednesday, partnering with Walmart to supply in-store pickup of discounted vials of the drug for cash-paying sufferers.
The corporate is now betting on its closely-watched experimental weight problems tablet, orforglipron, to solidify its dominance within the area, particularly as Novo Nordisk and different drugmakers race to deliver their very own capsules or next-generation injections to the market.
On Thursday, Novo Nordisk launched a rival bid for U.S. weight problems biotech firm Metsera, hijacking a suggestion from Pfizer because it races to catch as much as Eli Lilly.
This story is growing. Please examine again for updates.

