Prenetics International Restricted (NASDAQ: PRE), headquartered in Hong Kong, is a well being sciences firm lively in genomics, diagnostics, and shopper well being. In an e-mail dialog with AlphaStreet, Prenetics’ CEO Danny Yeung mirrored on the corporate’s evolution and outlined its progress technique.
In a crowded genomics and diagnostics area, what differentiates Prenetics’ know-how and choices?

We’ve decisively remodeled from the medical diagnostics sector to pioneer a singular, direct-to-consumer well being ecosystem. The latest completion of our $72 million exit from ACT Genomics was the ultimate, pivotal step on this evolution, enabling us to dedicate our full assets to our high-growth shopper well being manufacturers. The cornerstone of our technique is IM8, which is on observe to turn into one of many fastest-growing complement manufacturers in trade historical past, projected to realize a $100 million annualized income run-rate (ARR) inside its first 12 months.
This isn’t merely one other complement model; the exceptional progress is a testomony to a disruptive mannequin that deeply resonates with customers. That is supported by an built-in ecosystem that features CircleDNA, our main direct-to-consumer DNA take a look at. This mixture permits us to supply a holistic shopper journey—from genetic insights to premium dietary supplements. Moreover, our differentiation is validated by exceptionally sturdy and sustainable unit economics. IM8 has demonstrated a buyer lifetime worth to acquisition value (LTV/CAC) ratio of 4.8x, a subscription price exceeding 80%, and a gross margin of 60%. This monetary self-discipline and buyer loyalty, mixed with the highly effective model recognition fostered by our partnership with David Beckham and world ambassadors like Aryna Sabalenka, essentially units us other than any competitors.
What’s your long-term imaginative and prescient for Prenetics in preventive healthcare?
We would like customers to take full management of their well being and wellness journey. We’re transferring past the standard reactive mannequin of healthcare to create a future the place people are proactive in enhancing their life’s vitality and resilience via personalised, science-backed options. This imaginative and prescient is centered on constructing IM8 into one of many world’s most trusted and accessible well being and wellness manufacturers.
Having already delivered over 10 million servings and positively impacted lots of of hundreds of lives, IM8 represents our dedication to creating high-quality vitamin accessible to customers globally. Our method with IM8 is to mix rigorous scientific formulation with distinctive buyer expertise, guaranteeing that preventive healthcare turns into not simply efficient but additionally handy and sustainable for on a regular basis customers. This focus permits us to scale our influence whereas sustaining the standard that units IM8 aside within the crowded wellness market.
What are the largest challenges in scaling the corporate globally?
Our technique proactively addresses essentially the most vital hurdles, reminiscent of market penetration and operational effectivity, via decisive motion and confirmed execution. As an illustration, buyer acquisition and market penetration in new territories might be complicated and expensive. Nevertheless, IM8’s outstanding progress, with a compound annual progress price exceeding 2,400% in its first 9 months, demonstrates a extremely environment friendly and scalable buyer acquisition engine.
Our mannequin, which leverages refined efficiency advertising and marketing methods and maintains a buyer acquisition value of simply $104, has confirmed to be extremely efficient. This offers us a transparent and repeatable playbook for getting into new markets. We additionally constantly optimize our logistics prices via strategic partnerships, bulk delivery preparations, and automatic fulfilment processes. Having already processed over 350,000 buyer purchases, now we have refined our operations to realize value efficiencies that enhance our unit economics whereas sustaining quick supply instances. Our debt-free steadiness sheet, sturdy money place with greater than $90m in money and Bitcoin gives us with the monetary flexibility to spend money on these operational optimizations with out compromising our progress trajectory.
How shut is the corporate to reaching sustained profitability, and what key levers will get you there?
We communicated our timeline to realize break-even within the first quarter of 2026. The first driver is the exponential progress and compelling unit economics of our flagship shopper model, IM8. With a transparent trajectory to surpass $100 million in Annual Recurring Income and first-half 2025 income progress of 452%, IM8 is our core income engine. Extra importantly, that is high-quality, sustainable income. The model’s 56% gross margin, mixed with an 80%+ subscription price, gives a robust basis of high-margin, recurring income that’s vital for long-term profitability. One other key lever is our disciplined operational effectivity.
Our LTV/CAC ratio of 4.8x signifies that we’re buying high-value, loyal prospects in a extremely worthwhile method. We’re additional optimizing our buyer acquisition by localizing our promoting campaigns, transferring past English-only content material to raised resonate with various world markets and enhance conversion charges. Moreover, our strategic resolution to divest from the medical diagnostics sector has streamlined our operations, eliminating a supply of money burn and permitting us to focus our whole group on the high-growth, high-margin shopper well being section. This focus considerably accelerates our path to profitability. These levers are supported by a debt-free steadiness sheet and a robust money place, which allow us to execute our progress technique from a place of monetary power, guaranteeing our journey to profitability is each fast and sustainable.
What strategic benefit does Prenetics see in holding Bitcoin as a part of its treasury and the newest Bitcoin-per-day technique?
At Prenetics, our Bitcoin technique is rooted in a long-term conviction about the way forward for sound cash and monetary sovereignty. We view Bitcoin because the world’s most safe, decentralized, and scarce asset — one which serves as a strategic hedge towards fiat forex debasement and world macro uncertainty. Since initiating our Bitcoin accumulation program in June, we’ve constructed holdings of 255 BTC, now valued at over US$31 million, representing unrealized positive factors of roughly US$3.8 million. With greater than US$60 million in money and 0 debt, we keep one of many strongest steadiness sheets in our sector.
Our ongoing buy of 1 BTC per day displays our disciplined, programmatic method to constructing a generational treasury asset. We plan to proceed this technique via the rest of the 12 months and are evaluating alternatives to additional enhance the speed of our Bitcoin acquisitions over time. Finally, our Bitcoin technique is an extension of our core mission — to assist individuals construct each well being and wealth for the long run. As we pioneer breakthroughs in longevity science via IM8 and strengthen our monetary basis via Bitcoin, we’re aligning two of essentially the most highly effective forces shaping the longer term: optimized well being span and sound cash.

